Perturbation Monte Carlo methods to solve inverse photon migration problems in heterogeneous tissues.
نویسندگان
چکیده
We introduce a novel and efficient method to provide solutions to inverse photon migration problems in heterogeneous turbid media. The method extracts derivative information from a single Monte Carlo simulation to permit the rapid determination of rates of change in the detected photon signal with respect to perturbations in background tissue optical properties. We then feed this derivative information to a nonlinear optimization algorithm to determine the optical properties of the tissue heterogeneity under examination. We demonstrate the use of this approach to solve rapidly a two-region inverse problem of photon migration in the transport regime, for which diffusion-approximation-based approaches are not applicable.
منابع مشابه
Perturbation and differential Monte Carlo methods for measurement of optical properties in a layered epithelial tissue model.
The use of perturbation and differential Monte Carlo (pMC/dMC) methods in conjunction with nonlinear optimization algorithms were proposed recently as a means to solve inverse photon migration problems in regionwise heterogeneous turbid media. We demonstrate the application of pMC/dMC methods for the recovery of optical properties in a two-layer extended epithelial tissue model from experimenta...
متن کاملThe Study of Variation of Photon Intensity Inside Biological Phantom by Green Theorem
The Image reconstruction is an important problem in optical tomography. The process of the image processing requires the study of photon migration in biological tissue. There are several approaches to study and simulate propagation of photons in biological tissues. These approaches are categorized into stochastic and analytical groups. The Monte Carlo method as a stochastic method is widely use...
متن کاملMonte Carlo Modeling of Dual and Triple Photon Energy Absorptiometry Technique
Introduction: Osteoporosis is a bone disease in which there is a reduction in the amount of bone mineral content leading to an increase in the risk of bone fractures. The affected individuals not only have to go through lots of pain and suffering but this disease also results in high economic costs to the society due to a large number of fractures. A timely and accurate diagnosis of this disea...
متن کاملApplication of MCNP4C Monte Carlo code in radiation dosimetry in heterogeneous phantom
Background: In treating patients with radiation, the degree of accuracy for the delivery of tumor dose is recommended to be within ± 5% by ICRU in report 24. The experimental studies have shown that the presence of low-density inhomogeneity in areas such as the lung can lead to a greater than 30% change in the water dose data. Therefore, inhomogeneity corrections should be used in treatment pla...
متن کاملThe effect of electronic disequilibrium on the received dose by lung in small fields with photon beams: Measurements and Monte Carlo study
Background: Prediction of the absorbed dose in irradiated volume plays an important role in the outcome of radiotherapy. Application of small fields for radiotherapy of thorax makes the dose calculation process inaccurate due to the existence of electronic disequilibrium and intrinsic deficiencies in dose calculation algorithms. To study the lung absorbed dose in radiotherapy with smal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Optics letters
دوره 26 17 شماره
صفحات -
تاریخ انتشار 2001